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What Is Neuropathy? What Causes Neuropathy?

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Neuropathy is a party of disorders that occurs when nerves of the peripheral fitful system (the part of the disturbed method outside of the brain and spinal cord) are damaged. The example is generally referred to as peripheral neuropathy, and it is most commonly due to damage to nerve axons. Neuropathy normally causes heartache and numbness in the hands and feet. It can result from traumatic injuries, infections, metabolic disorders, and exposure to toxins. One of the most popular causes of neuropathy is diabetes.
Neuropathy can affect nerves that governance muscle movement (motor nerves) and those that detect sensations such as coldness or pain (sensory nerves). In some cases - autonomic neuropathy - it can alter internal organs, such as the heart, blood vessels, bladder, or intestines.
Agony from peripheral neuropathy is usually described as a tingling or burning sensation. There is no particular length of future that the hurt exists, but symptoms often augment with generation - mainly if the neuropathy has an underlying condition that can be cured. The action is much associated with damaging nutrition, a figure of diseases, and pressure or trauma, nevertheless multifarious cases keep no known generalization (called idiopathic neuropathy).
In the United States, about 20 million people suffer from neuropathy. Over half of diabetes patients further suffer from the condition.

How is neuropathy classified?

Peripheral neuropathy can be broadly classified into the following categories:
  • Mononeuropathy - involvement of a unmarried nerve. Examples include carpal tunnel syndrome, ulnar nerve palsy, radial nerve palsy, and peroneal nerve palsy.
  • Multiple mononeuropathy - two or and nerves individually affected.
  • Polyneuropathy - generalized involvement of peripheral nerves. Examples include diabetic neuropathy and Guillain-Barre syndrome.
Neurophathies may very be categorized based on a functional classification (motor, sensory, autonomic, or mixed) or the type of inception (acute - hours or days, subacute - weeks or months, or chronic - months or years).
The most accepted anatomy of neuropathy is (symmetrical) peripheral polyneuropathy, which remarkably affects the feet and legs on both sides of the body.

What causes neuropathy?

Approximately 30% of neuropathy cases are considered idiopathic, which means they are of unknown cause. Another 30% of neuropathies are due to diabetes. In fact, about 50% of bodies with diabetes develop some type of neuropathy. The remaining cases of neuropathy, called acquired neuropathies, keep distinct imaginable causes, including:
  • Trauma or impact on nerves, recurrently from a lob or crutch or repetitive motion such as typing on a keyboard

  • Nutritional problems and vitamin deficiencies, regularly from a lack of B vitamins

  • Alcoholism, repeatedly through dirt poor dietary habits and vitamin deficiencies

  • Autoimmune diseases, such as lupus, rheumatoid arthritis, and Guillain-Barre syndrome

  • Tumors, which often press up against nerves

  • Other diseases and infections, such as kidney disease, liver disease, Lyme disease, HIV/AIDS, or an underactive thyroid (hypothyroidism)

  • Inherited disorders (hereditary neuropathies), such as Charcot-Marie-Tooth disease and amyloid polyneuropathy

  • Poison exposure, from toxins such as heavy metals, and decided medications and cancer treatments

Who gets neuropathy?

Risk factors for peripheral neuropathy include diverse conditions and behaviors. Heads with diabetes who poorly control their blood sugar levels are very feasible to suffer from some neuropathy. Autoimmune diseases such as lupus and rheumatoid arthritis also development one's chance of developing a neuropathy. Citizens who include received organ transplants, AIDS patients, and others who own had some type of unsusceptible step suppression admit a higher risk of neuropathy. In addition, those who abuse alcohol or have vitamin deficiencies (especially B vitamins) are at an increased risk. Neuropathy is and extra practicable to occur in tribe with kidney, liver or thyroid disorders.

What are the symptoms of neuropathy?

Neuropathy symptoms depend on indefinite factors, principally where the affected nerves are located and which type of nerves are affected (motor, sensory, autonomic). Assorted types of neuropathy impinge all three types of nerves. Some neuropathies suddenly occur while others come on gradually over the plan of years.
Motor nerve damage usually leads to symptoms that affect muscles such as muscle weakness, cramps, and spasms. It is not meagre for this type of neuropathy to example to a loss of balance and coordination. Patients may find it hard to march or run, tactility like they compass weighty legs, stumble, or tire easily. Damage to arm nerves may build it difficult to do routine tasks comparable carry bags, unbolted jars, or turn door knobs.
Sensory nerve damage can foundation various symptoms, such as an impaired belief of position, tingling, numbness, pinching and pain. Pain from this neuropathy is often described as burning, freezing, or electric-like, and copious announcement a sensation of draining an invisible "glove" or "stocking". These sensations tend to be worse at night, and can convert painful and sever. On the contrary, sensory nerve damage may model to a lessening or absence of sensation, where nothing at all is felt.
Autonomic nerve damage affects internal organs and involuntary functions and can lead to abnormal blood pressure and love rate, reduced bent to perspire, constipation, bladder dysfunction, diarrhea, incontinence, sexual dysfunction, and thinning of the skin.

How is neuropathy diagnosed?

Peripheral neuropathy is frequently not elementary to diagnose. It is not a single disease, on the contrary a symptom with often several doable causes. The customary diagnostic action begins with a adequate medical history with physical and neurological exams that will scrutinize tendon reflexes, muscle impact and tone, the intelligence to observe sensations, and posture and coordination. Blood tests are also common in order for doctors to degree levels of vitamin B-12. Other common tests include urinalysis, thyroid function tests, and a nerve conduction peruse that includes electromyography (to measure electrical discharges produced in muscles). Physicians may further recommend a nerve biopsy, where a small portion of nerve is removed and examined under a microscope.

How is neuropathy treated?

There are a array of treatments available for peripheral neuropathy. They range from traditional pills and creams to special diets and therapies that stimulate the fearful system. Antidepressants, principally tricyclics and selective serotonin-norepinephrine re-uptake inhibitors (SNRI's), are a favoured treatment for neuropathies. They testament aid neuropathic distress in non-depressed persons. Another class of medicines commonly prescribed for neuropathy is that of anticonvulsants. These medicines block calcium channels on neurons to borderline pain. Opioid narcotic treatments for neuropathy are used as hardy to treat the condition, but are less favored because of the risk of dependency. However, opioids hog been the most consistently forcible in reducing pain.
For some types of neuropathy, such as post-herpes neuralgia, physicians recommend treatment with a topical anesthetic such as lidocaine. Topical applications of capsaicin (the chemical that makes peppers hot) has as well been used to treat neuropathic pain.
Alternative therapies for peripheral neuropathy include cannabinoids (an party of chemicals establish in marijuana), Botulinum Toxin Type A (better hackneyed as Botox), NMDA antagonists (such as ketamine), dietary supplements (such as alpha lipoic and benfotiamine), chiropractic massages, yoga, meditation, cognitive therapy, and accupuncture.
A ending class of therapies for neuropathy are called neuromodulators. These include both implantable and non-implantable technologies (electrical and chemical) such as spinal cord stimulators, implanted spinal pumps, electrodes that stimulate the engine cortex of the brain, and methods called broad brain stimulation.

How can neuropathy be managed and prevented?

There are several ways to designate neuropathy and prevent its symptoms. Good foot health is important, especially for diabetics. Patients should test feet for blisters, cuts, or calluses and avoid tight becoming shoes and socks. Doctors can recommend an application ground plan that will reduce neuropathy pain and bridle blood sugar levels. Patients should besides leave smoking and eat healthful meals. Massages of hands and feet may also aid neuropathy management by stimulating nerves and temporarily relieving pain. Finally, it is advised to avoid prolonged pressure on knees or elbows in codification to prevent new nerve damage.

Video - What is Neuropathy?


Written by Peter Crosta M.A.
View drug information on Botox Cosmetic.
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