A unique programme to support a UK-wide network of hospital organ donation "champions" is to be launched next week. The programme is designed for the growing number of Clinical Leads for Organ Donation and the Donation Committee Chairs who work along side them. These people have been appointed to key roles in hospitals to implement recommendations made by the Organ Donation Taskforce and help increase donation rates by 50% over a five-year period. Presently 170 clinical leads throughout the UK dedicate time every week to working with colleagues in intensive care units and emergency medicine departments to encourage organ donation to be viewed as part of normal, every day practice in hospitals.
The largest randomised study comparing the effect of type of transplant on survival is published Online First in The Lancet Oncology. It reports that patients transplanted with peripheral blood stem cells (PBSC) have no difference in survival compared with patients given bone marrow after ten years. Bone marrow transplants involve the collection of stem cells from the bone marrow. In peripheral blood stem cell transplantation (PBSCT) stem cells are collected from the donor's blood and this avoids the complications of bone marrow collection such as surgery and anaesthesia. Earlier studies have had fairly short follow-ups of three to four years.
Minimally Invasive Adult Liver Donation For Pediatric Transplantation Available Exclusively At NewYork-Presbyterian Morgan Stanley Children's Hospital
NewYork-Presbyterian Morgan Stanley Children's Hospital is the only medical center in the United States to offer minimally invasive liver donation for pediatric transplantation. Surgeons use a laparoscopic technique to remove a section of liver from a living donor for implantation in a pediatric patient -- typically a parent donating to their child. The innovative approach promises dramatically improved recovery for the donor. The laparoscopic liver retrieval is offered by Dr. Benjamin Samstein, a transplant surgeon at NewYork-Presbyterian Morgan Stanley Children's Hospital and NewYork-Presbyterian Hospital/Columbia University Medical Center, and assistant professor of surgery at Columbia University College of Physicians and Surgeons.
Geisinger Medical Center (GMC) was recently designated a National Marrow Donation Program (NMDP) collection site, becoming the only site in the region to collect bone marrow or blood stem cells from willing donors. "It is very exciting and a major achievement to be designated a National Marrow Donation Program collection site, " said Edward Gorak, D.O., Medical Oncologist/Hematologist and Co-Director of the Bone Marrow Transplant Program at GMC. "Willing bone marrow donors will no longer have to travel long distances to reach a collection site, and we are hopeful that as donating becomes more accessible, more individuals will be willing to donate.
Although transplantation of pancreatic islets is an attractive way to treat type 1 diabetes, early islet loss soon after transplantation has limited its clinical use. By studying islet transplantation in a mouse model of diabetes, a team of researchers, at the RIKEN Research Center for Allergy and Immunology, Japan, and Fukuoka University, Japan, has now identified a potential new set of targets to improve the efficiency of pancreatic islet transplantation. Previous studies have identified an immune mechanism essential for early loss of transplanted islets: immune cells expressing the proteins Gr-1 and CD11b produce the soluble molecule IFN-gamma in a process that is dependent on immune cells known as NKT cells.
The California Heart Center, the cardiology group that developed the nation's largest heart transplant program, has joined the Cedars-Sinai Heart Institute and Cedars-Sinai Medical Care Foundation. The California Heart Center physicians, who are nationally and internationally regarded for their expertise in treating advanced heart failure, are moving from UCLA to assume leadership roles at the Cedars-Sinai Heart Institute. Their group, which will remain in private practice, will also become part of the Cedars-Sinai Medical Care Foundation. The group is led by Jon Kobashigawa, M.D., a past president of the International Society for Heart and Lung Transplantation who has authored more than 200 scientific manuscripts.