Rates In Risk Factor For Breast Cancer, Atypical Ductal Hyperplasia, Fell In Line With Hormone Therapy Decline, US Study
Researchers in the US found that the decline in use of postmenopausal hormone therapy may partly explain the fall in incidence of a known risk factor for breast cancer, atypical ductal hyperplasia. They also said their findings support the idea that low and high grade breast cancers develop via different pathways and thereby clarify the role that hormone therapy may play in increasing the rates of breast cancer. The study was the work of first author Dr Tehillah Menes, and colleagues and is published in the November issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. Menes, who during the study was the chief of breast service in the Department of Surgery at Elmhurst Hospital Center, New York, told the press that: "Postmenopausal hormone treatment is associated with increased rates of benign breast biopsies, and early and late stages of cancer ." "Atypical ductal hyperplasia is associated with the use of postmenopausal hormone treatment and its rates have decreased with the decline in use of this treatment, " she added.
Women who have an early menopause are unlikely to have a long term increased risk of hip fractures associated with menopausal bone density weakening, according to a new study from The Australian National University. For decades medical practitioners have understood a link between menopause and a decrease in bone density. This has translated into clinicians advising women who had an early menopause that they are at particularly high risk of hip fracture - a common complaint amongst the elderly. The study, led by Associate Professor Emily Banks of the National Centre for Epidemiology and Population Health at ANU, has found that age is the main determinant of hip fracture and that among the elderly their age at menopause has little, if any, effect on hip fracture risk. Hence, doctors should base their advice on the age of patients alone. The researchers used data from the UK's Million Women Study to reach their findings. The Million Women Study recruited 1.3 million women aged 50-64 years who attended breast cancer screening clinics between 1996 and 2001 to investigate how reproductive and lifestyle factors affect women's health.
New Mayo Clinic research has found that robotic surgery for vaginal prolapse ( http://www.mayoclinic.org/pelvic-organ-prolapse/ ) dramatically reduces patient hospital stay and recovery time. These findings are being presented this week at the North Central Section of the American Urological Association in Scottsdale, Ariz. Vaginal prolapse is a condition in which structures such as the uterus, rectum, bladder, urethra, small bowel, or the vagina itself may begin to prolapse, or fall, from their normal positions. Without treatment or surgery, these structures may eventually prolapse farther into the vagina or even through the vaginal opening if their supports weaken enough. "Vaginal prolapse is a common, yet distressing physical and cosmetic condition that 10 percent of women will suffer in their lifetimes, " says Daniel Elliott, M.D., ( http://www.mayoclinic.org/bio/11774568.html ) Mayo Clinic urologist and senior author on the study. "Robotic sacrocolpopexy surgery appears to offer many new benefits for patients -- including decreased hospital stay and quicker recovery.
A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion. "Easy access and good communication among surgeons, medical oncologists and reproductive endocrinologists is critical, " said Lynn Westphal, MD, associate professor, department of obstetrics and gynecology, Stanford University School of Medicine, Stanford, CA. Frequently, young women who are diagnosed with breast cancer must make difficult decisions about surgical treatment options as well as chemotherapeutic treatments that may permanently impair their fertility or delay childbearing. Advancements in reproductive medicine such as in vitro fertilization have benefited young women with breast cancer. "The burden of facing premature menopause adds to the stress experienced by young cancer survivors, " said Irene Wapnir, MD, FACS, associate professor, department of surgery, Stanford University School of Medicine.
A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists. Though the studies have not been conducted to determine recommended consumption amounts, scientists say the compound, called trigonelline or "trig, " may be a factor in estrogen-dependent breast cancer but beneficial against colon cancer development. "The important thing to get from this is that 'trig' has the ability to act like a hormone, " said Dr. Clinton Allred, AgriLife Research nutrition scientist. "So there is a tie to cancer in the sense that we are looking at estrogen-dependent cancer cells. But that doesn't suggest that it would actually cause the disease. I don't believe there should be any concern about drinking coffee at this point." His report was published in the Journal of Nutrition. Allred's lab studies dietary compounds that can mimic the hormone estradiol - the primary hormone in women. His main focus has been to look at how estrogen protects against the development of colon cancer.
A menopause-cardiology consensus statement has called for direct action to prevent cardiovascular disease (CVD) in menopausal women. The statement also concludes that there is little evidence of increased CVD risk in taking HRT. The International Menopause Society consensus statement was developed at a Workshop** between menopause specialists and cardiologists. The Task Force on Gender of the European Society of Cardiology participated in the Workshop. The statement was published in current issue of the peer-reviewed journal Climacteric. The main messages of the Workshop are: Many women and their doctors are unaware of the cardiovascular dangers facing women going through and after the menopause. Awareness of the dangers needs to be raised; CVD is the number-one killer of women in the Western world and women should be assessed for CVD and the risk factors for CVD on visits to their gynaecologist. The effects of hormone replacement therapy (HRT) on CVD are favourable, although these depend on the woman's age and medical background.
Animal studies suggest that adding flaxseed oil to the diet could reduce the risk of osteoporosis in post-menopausal women and women with diabetes, according to a report to be published in the International Journal of Food Safety, Nutrition and Public Health. Mer Harvi and colleagues at the National Research Center, in Cairo, Egypt, have studied the effect of diabetes on bone health and evaluated how flaxseed oil in the diet might delay the onset of osteoporosis. The researchers studied 70 female albino rats of which 30 had their ovaries removed (ovx) to simulate the post-menopausal state and experimental diabetes was present in one group of rodents. The researchers then classified the rats as control, sham, diabetic, diabetic received flaxseed oil in the diet, ovx, ovx-diabetic and ovx-diabetic received flaxseed oil in the diet. After two months, the team collected urine and blood samples from the rats and measured serum insulin-like growth factor 1 (IGF-1) and the bone-creating protein osteocalcin.
Scientists in Korea fashion that people with osteoporosis, a disease that lowers bone density and increases risk of fracture, are extremely bounteous likely to have vertigo, a dizziness disorder caused by problems in the inner ear. The study was the effort of Dr Ji Soo Kim, of Seoul National University School of Medicine in Korea, and colleagues, and is published in the 24 March point of the gazette Neurology. For the study, Kim and colleagues examined 209 people with balmy positional vertigo (BPV) for which there was no known cause and compared them with 202 mankind with no version of dizziness (the controls). BPV can sometimes result from ear surgery or purpose trauma and is thought to be when crystals of calcium carbonate become loose and step on all sides of in the tubes of the inner ear that guidance people to balance. For the osteoporosis data, the researchers used the bone mineral density measures of front and back lumbar backbone and femur of the participants. After adjusting for age, sex, alcohol, smoking, and hyperphosphatemia (a condition that can again lower calcium levels), the results showed that nation with low bone density, or osteoporosis, were three times amassed imaginable to have vertigo than people with general bone density.
Delivery Of Rx Oestrogen Terminated The Skin May Show Safety Benefits As Opposed To Uttered Delivery
Transdermal delivery of estrogen therapy available by prescription "seems not to alter" the risk of venous thromboembolism (VTE), or blood clotting, in postmenopausal patients when compared to oral delivery, a dewy study suggests. The discover was conducted by researchers at NYU Langone Medical Center and was published in the virgin theory of Menopause: The Journal of the North American Menopause Society. Prescription transdermal estrogen therapy is bioidentical to estrogen produced by a woman's ovaries before menopause and delivered through the skin. Transdermal estrogen is available in a variety of formulations which have been grade controlled and approved guarded and effective by the United States Food and Drug Administration (FDA). The club at NYU Langone sought to drive the object of delivery of estrogen therapy on postmenopausal women. Blood obtained from 84 postmenopausal women was tested for clotting action before and after control of verbal or transdermal estrogen for a space of eight weeks.
"Broken love syndrome" is much a question to multifarious in the medical community, on the contrary virgin data from researchers at The Miriam Hospital may shed some cloudless on the clinical characteristics and outcomes of this relatively rare, life-threatening condition. Researchers created a registry of 70 patients with the syndrome, declared medically as Takotsubo cardiomyopathy, who were diagnosed between July 2004 and April 2008. Two-thirds of the patients - almost all post-menopausal women - had experienced a very stressful physical or emotional act aloof before arriving at the hospital with emotions attack-like symptoms. Although 20 percent were critically sick and required emergency treatment to keep them alive, all patients survived the first 48 hours and experienced a unabridged and complete recovery, The announcement is published in the Apr 1 problem of the American Journal of Cardiology. "It can be difficult for cardiologists and emergency room physicians to diagnose and captain patients with broken heart syndrome.