Becoming "hard of hearing" is a standard but unfortunate part of aging: A syndrome called age-related hearing loss affects about 40 percent of people over 65 in the United States, and will afflict an estimated 28 million Americans by 2030. "Age-related hearing loss is a very common symptom of aging in humans, and also is universal among mammal species, and it's one of the earliest detectable sensory changes in aging, " says Tomas Prolla, a professor of genetics and medical genetics at the University of Wisconsin-Madison. Prolla is senior author of a paper in today's (Nov. 9) PNAS that looks at the genetic roots of this type of hearing loss, which is not due to noise exposure. The study has identified a gene that is essential to age-related hearing loss, a condition marked by deaths of sensory hair cells and spiral ganglion neurons in the inner ear. These cells are at the heart of the conversion of vibrations into nerve impulses that the brain can decipher, and yet these cells cannot be regenerated.
What do you get when you cross a mouse with poor hearing and a mouse with even worse hearing? Ironically, a new strain of mice with "golden ears" - mice that have outstanding hearing as they age. The work by one of the world's foremost groups in age-related hearing loss, or presbycusis, marks the first time that scientists have created the mouse equivalent of a person with "golden ears" - people who are able to retain great hearing even as they grow older. The research at the University of Rochester Medical Center was published online recently in the journal Neurobiology of Aging. The new mouse is expected to offer clues about how these lucky folks are able to retain outstanding hearing even through old age. Researchers estimate that approximately 5 percent of people, mainly women, fall into this category. The new mice created in the laboratory of Robert Frisina, Ph.D., embody many of the same traits of human "golden ears" because of an astute cross of two types of mice long popular with researchers.
New research reveals that children with developmental dyslexia have a deficit in a brain mechanism involved in the perception of speech in a noisy environment. The study, published by Cell Press in the November 12 issue of the journal Neuron, provides the first direct evidence that the human auditory brainstem exhibits remarkable moment-to-moment plasticity and undergoes a fine tuning that is strongly associated with noise exclusion. Most people have little trouble carrying on a conversation with a friend in a noisy restaurant thanks to the highly adaptive auditory system which manages to focus in on the predictable, repeating pitch of the friend's voice and effectively tune out the random, fluctuating background noise. Although it may be a routine occurrence, exactly how the nervous system manages to accomplish this feat is still a mystery. "Understanding the relationship between the adaptive auditory system and perception of speech in noise is clinically relevant because recent studies have demonstrated that the 5% of school-age children who are diagnosed with developmental dyslexia can be particularly vulnerable to the deleterious effects of background noise, " explains senior study author Dr.
The vast majority of school-aged children can focus on the voice of a teacher amid the cacophony of the typical classroom thanks to a brain that automatically focuses on relevant, predictable and repeating auditory information, according to new research from Northwestern University. But for children with developmental dyslexia, the teacher's voice may get lost in the background noise of banging lockers, whispering children, playground screams and scraping chairs, the researchers say. Their study appears in the Nov. 12 issue of Neuron. Recent scientific studies suggest that children with developmental dyslexia - a neurological disorder affecting reading and spelling skills in 5 to 10 percent of school aged children - have difficulties separating relevant auditory information from competing noise. The research from Northwestern University's Auditory Neuroscience Laboratory not only confirms those findings but presents biological evidence that children who report problems hearing speech in noise also suffer from a measurable neural impairment that adversely affects their ability to make use of regularities in the sound environment.
Maney Publishing is pleased to announce the purchase of two quarterly journals from John Wiley & Sons, Ltd: Cochlear Implants International and Deafness & Education International, which together establish a decisive publishing commitment to the clinical treatment and education of the deaf. The acquisition also reflects Maney's continuing involvement and expertise in publishing for specialist societies and professional organisations. Deafness & Education International is the official publication of both the British Association for Teachers of the Deaf (BATOD) and the National Association of Australian Teachers of the Deaf (NAATD). Cochlear Implants International is endorsed by the British Cochlear Implants Group. Maney's Publishing Director, Mark Simon, is delighted by the acquisition of these two titles: "The new journals represent a move into two complementary subject specialities, and come with important publishing alliances, and good prospects for Maney and all those involved in the journals.
Scientists of Helmholtz Zentrum MГ nchen, led by Professor Martin HrabГ de Angelis, director of the Institute of Experimental Genetics, have developed a distinct mouse model with a genetic mutant in which a unmarried base of a specific microRNA seed region has been altered. Mice carrying this miR-96 mutation suffer progressive hearing loss as they dispose older. Moreover, if they carry two of these mutants, their sensory hair cells are impaired from birth on. A number of genes associated with hearing loss were already known. "However, we were very surprised when with our late mouse replica we discovered this dewy class of genes - microRNA - as genetic create for this clinical picture, " explained Dr. Helmut Fuchs, who conceived the doctrine of this mouse imitation and who is scientific-technical tendency of the German Mouse Clinic at Helmholtz Zentrum MГ nchen. The new mouse mould is called diminuendo, named after the vocable in music theory thought "becoming gradually softer".
Hearing loss is a common disorder that can basis significant indication difficulties and directly affect the accurate transfer of information during a medical encounter. Hearing loss besides often increases with age; as the Baby Boomers purchase older, the prevalence of hearing loss will increase. Documentation of hearing loss in the electronic medical record (EMR) can remind physicians that it is necessary to accommodate patients' communication needs and thus improve the standard of interpersonal interplay and advice transmission between patients and physicians. Common use of EMR at the Massachusetts Eye and Ear Infirmary and Massachusetts Usual Hospital offered researchers the opportunity to document known primary binaural (in both ears) hearing loss in notes summarizing abundant medical histories and physical examinations. Their findings are outlined in the Apr 2009 issue of the Journal of Regular Internal Medicine and were published earlier on line. http://www.springerlink.com/content/l7756224175662l1/ Researchers retrospectively screened the charts of all patients (approximately 1, 200) who underwent audiometry (hearing testing) in the audiology branch at Mass.
Virginia Commonwealth University School of Medicine researchers get discovered that male animals with hearing loss actually re-route the belief of touch into the hearing parts of the brain. In the study, published online in the Early Edition of the Proceedings of the National Academy of Sciences the week of March 23, the team reported a phenomenon known as cross-modal plasticity in the auditory course of adult animals. Cross-modal plasticity refers to the replacement of a damaged sensory system by one of the remaining ones. In this case, the impression of hearing is replaced with touch. Approximately 15 percent of American adults suffer from some conformation of hearing impairment, which can significantly impact quality of life, exceptionally in the elderly. "One repeatedly learns, anecdotally, that 'grandpa' simply turned off his hearing support since it was confusing and no longer helped. Our scan indicates that hearing deficits in adult animals result in a conversion of their brain's sound processing centres to respond to another sensory modality, production the interpretation of residual hearing even another difficult, " said principal investigator Alex Meredith, Ph.
Cochlear Americas, the world's dean in advanced hearing technologies, brings in sync cochlear implant recipients and their families for the third Cochlear Celebration on March 26-29 in Anaheim, California. With over 600 recipients and their families expected to attend, this inspiring four-day event is the largest gathering of cochlear implant recipients in the world. Celebration 2009 offers educational sessions and a variety of activities designed to teach recipients and their families how to maximize the use of Nucleus(R) cochlear implants, a small electronic device designed to restore hearing to someone with severe-to-profound hearing loss. "Celebration 2009 demonstrates our commitment to our cochlear implant recipients in helping them close their personal best, " said Chris Smith, President, Cochlear Americas. "This bracing case offers recipients the particular opportunity to be in the company of so many others who have experienced their corresponding miraculous journey of regaining hearing.
New research has identified visiting grandchildren as the main reason grandparents decide to have their hearing tested for the headmost time. Hearing specialist, Amplifon, who commissioned the research, form that the biggest single trigger for retirement period people to do something approximately hearing loss is the 'feeling of social exclusion' from not hearing their grandchildren clearly. "High closeness hearing loss, in particular children's voices, is usually the first to be noticed, " explains Enrico Vacca, marketing director of Ampifon UK. "According to The Grandparents' Association, 82 per cent of children are regularly cared for by their grandparents and the breakdown in notice caused by gradual hearing loss is persuading those who may have been in denial about their hearing loss to chalk up a hearing test." There are 14 million grandparents in the UK and 6.5million community over the generation of 60 have some embodiment of hearing loss. Vacca added, "Not only are grandparents spending expanded continuance than ever with their grandchildren due to parents returning to adequate period work;