Health and Fitness

Sciele Introduces Adrenaclick trade; epinephrine Injection, USP Auto-Injector For The Emergency Treatment Of Anaphylaxis

Sciele Pharma, Inc., a Shionogi company, today announced the U.S. availability of Adrenaclick™ , a single-dose, epinephrine auto-injector for the emergency treatment for severe allergic reactions (Type I) such as anaphylaxis. Adrenaclick™ will be available as a single unit or a convenient Two-Pack. It is also available in two dosing options (0.15 mg and 0.3 mg). Adrenaclick™ delivers epinephrine, the drug of choice for anaphylactic reactions, with the use of an auto-injector. The Adrenaclick™ auto-injector is designed to ensure accurate delivery of epinephrine in the thigh through a "press-and-hold" administration technique. It is also designed for ease-of-use with clearly labeled caps, a red injector tip, and color-coded instructions on the side of the unit. Sciele is also offering free training information to help educate patients on the proper administration; full details are available online at http://www.adrenaclick.com. Indication Adrenaclick™

Allergy Vaccinations Reduce Children's Health Care Costs By One-Third

Allergy immunotherapy, generally referred to as allergy vaccinations or shots, reduce total health care costs in children with allergic rhinitis (hay fever) by one-third, and prescription costs by 16 percent, according to a study published this month in Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI). "This large-scale, comparative effectiveness study of health outcomes clearly demonstrates the benefits of allergen immunotherapy for children with allergic rhinitis, " said Cheryl Hankin, Ph.D., president and chief scientific officer of BioMedEcon, and lead author of the study. "Findings are even more impressive, considering the results were based on 'real world' healthcare delivery, rather than on treatment provided within a tightly controlled clinical trial." The 10-year U.S. retrospective study is the first to show significant health care cost reductions in as early as three months and continued decreases over an 18-month period.

Osteopontin Contributes To Allergic Contact Dermatitis

Dr. Johannes M. Weiss and colleagues at the University of Ulm, Ulm, Germany have discovered that osteopontin (OPN) contributes to allergic contact dermatitis. They present these findings in the January 2010 issue of the American Journal of Pathology. Allergic contact dermatitis is a hyperreaction of the immune system to either allergens or irritants on the skin, such as poison ivy, nickel, or latex. Contact dermatitis results in large, burning, and itchy rashes, which can take anywhere from several days to weeks to heal. Once allergic contact dermatitis occurs, only strict avoidance can prevent a recurrence, and there is no method to resist persistent sensitization. Seier et al hypothesized that OPN, an immune mediator that has been shown to worsen the effects of autoimmune disease, played a role in eliciting and facilitating chronic allergic contact dermatitis. They found that both skin cells and immune cells secreted OPN in allergic contact dermatitis lesions. OPN was strongly induced in antigen-specific immune cells in a murine model of chronic contact hypersensitivity, and OPN-deficient mice had a less severe chronic contact hypersensitivity response.

Imaging Tests Identify Role Of Allergies In Chronic Sinus Disease

Exposing patients with chronic sinus disease to allergens and then obtaining repeated images by X-ray or ultrasound reveals that nasal allergies may be involved in some cases of chronic sinus disease, according to a report in the December issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals. Chronic disease of the maxillary sinus (the sinus cavity located in the mid-face beneath the cheeks, on either side of the nose) is common and affects a wide population of adults and children, according to background information in the article. "Although the involvement of hypersensitivity mechanisms, and especially of nasal allergy, in chronic disease of the maxillary sinuses has been recognized, the diagnostic procedures for this disorder and the relationship vary, " the author writes. "There is a dearth of information regarding the direct causal involvement of hypersensitivity mechanisms of the nasal mucosa and potential consequences within the maxillary sinuses.

What Is Wheat Allergy? What Causes A Wheat Allergy?

People with a wheat allergy have an abnormal immune system response to at least one of the proteins that exist in wheat. It is one of the most common childhood food allergies, but may affect adults as well. The person with a wheat allergy has developed a specific antibody to a wheat protein, and sometimes more than one. People with wheat allergies can respond with a variety of possible signs and symptoms, including breathing difficulties, nausea, hives, bloated stomach and an inability to focus. With some people the consumption of wheat and wheat products may result in anaphylaxis - a life-threatening allergic response. The allergic reaction involves IgE (immunoglobulin) antibodies to at least one of the following proteins found in wheat: Albumin Globulin Gliadin Glutenin (gluten) Most allergic reactions involve albumin and globulin. Allergy to gliadin and gluten are less common. Gluten allergy is often confused with Celiac disease or some other digestive disorders. Some people have an allergic reaction when they inhale wheat flour, while others need to eat it in order to experience symptoms.

Your New Year's Celebration Can Cause More Than A Hangover

Toasting the New Year is a tradition that can cause more than a headache the next day. For some people, drinking may also trigger allergy and asthma symptoms, according to the American Academy of Allergy, Asthma & Immunology (AAAAI). "It is usually not the alcohol itself that produces the reaction. It is most likely ingredients, such as sulfur dioxide (metabisulfite), yeast and additives. Common allergic reactions include hives, skin rashes, flushing and warmth of the skin, bronchospasm or shortness of breath, especially in those with asthma, " according to Clifford W. Bassett, MD, FAAAAI, Chair of the Public Education Committee of the AAAAI. The key preservative in wine is sulfur dioxide. It is naturally produced by wine yeast in small quantities during fermentation. Sulfur dioxide is also used as a preservative in foods such as dried fruits, baked goods, condiments, canned foods, shellfish, frozen shrimp, canned tomatoes, frozen potatoes and fruit juices. If you tend to have a reaction to these foods, you may also experience it with wine.

Physicians Knowledge Of Childhood Food Allergies Lacking

With an estimated four to six percent of children in the U.S. suffering from food allergies, a new study shows that pediatricians and family physicians aren't always confident they have the ability to diagnose or treat food allergies. A study published in the January 2010 issue of Pediatrics and headed by Dr. Ruchi Gupta, M.D., M.P.H., a researcher at Children's Memorial Hospital and Assistant Professor of Pediatrics at Northwestern University's Feinberg School of Medicine, brought attention to current knowledge gaps among primary care physicians in the diagnosis and management of food allergy. Researchers at Children's Memorial used the Chicago Food Allergy Research Survey for Pediatricians and Family Physicians to analyze physicians' knowledge and perceptions of food-related allergies in children. More than 400 pediatricians and family physicians across the nation responded to questions in areas ranging from the definition and diagnosis of food allergy to appropriate treatment and use of healthcare among affected children.

The Down Side Of Romantic, Candle-Lit Dinners: An Unrecognized Source Of Indoor Air Pollution

Burning candles made from paraffin wax - the most common kind used to infuse rooms with romantic ambiance, warmth, light, and fragrance - is an unrecognized source of exposure to indoor air pollution, including the known human carcinogens, scientists report. Levels can build up in closed rooms, and be reduced by ventilation, they indicated in a study presented at the 238th National Meeting of the American Chemical Society (ACS). In the study, R. Massoudi Ph.D., and Amid Hamidi, Ph.D., said that that candles made from bee's wax or soy, although more expensive, apparently are healthier. They do not release potentially harmful amounts of indoor air pollutants while retaining all of the warmth, ambience and fragrance of paraffin candles (which are made from petroleum). "An occasional paraffin candle and its emissions will not likely affect you, " Hamidi said. "But lighting many paraffin candles every day for years or lighting them frequently in an un-ventilated bathroom around a tub, for example, may cause problems.

FDA Approves XYZAL R For Use In Children Age Six Months And Older For The Relief Of Perennial Allergic Rhinitis And Chronic Idiopathic Urticaria

UCB and sanofi-aventis U.S. announced that the U.S. Food and Drug Administration (FDA) has approved XYZAL(R) (levocetirizine dihydrochloride) for children age six months and older for the relief of symptoms of perennial allergic rhinitis (indoor allergies) and chronic idiopathic urticaria (chronic hives ) and for children age two years and older for symptoms of seasonal allergic rhinitis (outdoor allergies). Until now, XYZAL(R), a once-daily prescription antihistamine in both tablet and liquid formulations, has been used to treat symptoms of indoor and outdoor nasal allergies, as well as chronic idiopathic urticaria in patients age six years and older. "There are options for treating nasal allergies in young children, one of which is XYZAL(R). The availability of a liquid treatment with the established safety and efficacy of XYZAL(R) provides caregivers a new treatment option that can help relieve nasal allergy symptoms in young patients once diagnosed by a physician, " said Michael Blaiss, M.

The Government Of Canada Reminds Parents Of School Lunch Allergen Safety

As children head back to the classroom, Health Canada and the Canadian Food Inspection Agency are reminding parents of the importance of allergy awareness when packing lunches for their children. Severe allergic reactions can occur quickly and without warning, and some foods can be life-threatening to allergic children. As many as 1.2 million Canadians may be affected by allergies and these numbers are increasing, especially among children. Foods account for most children's allergies, with peanuts, tree nuts, sesame, soy, seafood (such as fish, crustaceans and shellfish), wheat, eggs and milk being the most common food allergens. When someone ingests even a tiny amount of an allergen, the symptoms of a reaction may develop quickly and can become very serious. The most dangerous symptoms include breathing difficulties, a drop in blood pressure, or shock, which may result in loss of consciousness and even death. Because of this, many elementary schools are now restricting certain foods from students' lunches.

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