Gene From Extinct Tasmanian Tiger Functions In Mouse
Genes extracted from the now extinct Tasmanian tiger (thylacine) havebeen inserted into a mouse, where they not only were synthesized butalso showed biological functionality. This is the first time afunctional response has been generated from DNA from an extinctspecies, and the results show that the protein, thylacine Col2a1, serves a similar function in the transgenic mouse as it did in theoriginal species.
Potential Vulnerabilities Discovered In HIV Infection
A new study reveals the genetic identity of human immunodeficiency virus (HIV), the version responsible for sexual transmission, in unprecedented detail.The finding provides important clues in the ongoing search for an effective HIV/AIDS vaccine, said researchers at the University of Alabama at Birmingham (UAB).
Among Hispanics And Caucasians Genes May Play Role In Risk Assessment For Prostate Cancer
Genetic differences may explain the greater risk for prostate cancer among Caucasian men compared with Hispanic men, which could help clinicians predict who is more likely to develop the disease, according to a paper published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Combination Of Genomics And Proteomics Yields A Surprising Finding: Silencing Foreign DNA In Bacteria
Compared to humans, bacteria have a much tidier genome. The tiny microorganisms pack their genes closely together, and don't carry around a lot of extraneous DNA, so-called junk DNA that fills in the gaps between genes. Some 90 percent of the complete genome sequence of the bacteria E.
Scientist Unravels Deadly Pathogens
A scientist in the Department of Biomedical Engineering at the University of Virginia Health System has deciphered the metabolic properties of two dangerous pathogens discovering how they thrive and which genes, when knocked out, cause them to weaken.
Study Finds That Those With A GLUT2 Gene Variation Consistently Consume More Sugars, Regardless Of Age Or Sex
A new study released in the online edition of Physiological Genomics finds that individuals with a specific genetic variation consistently consume more sugary foods. The study offers the first evidence of the role that a variation in the GLUT2 gene - a gene that controls sugar entry into the cells - has on sugar intake, and may help explain individual preferences for foods high in sugar.
How Tumorigenesis And Drug Design Are Affected By Mutant P53 Stability
In the May 15th issue of G&D, Dr. Guillermina Lozano (MD Anderson Cancer Center) and colleagues reveal how the stabilization of a mutated form of p53 affects oncogenesis, and lends startling new insight into the potential pitfalls of using Mdm2 inhibitors for cancer therapy.
Connecting Cancer Genes - Study Implicates 350 Gene Regions In Cancer Development In The Mouse, UK
A large genetic study in mice has identified hundreds of genes involved in the development of cancer by examining the DNA of more than 500 lymphomas to find the cancer causing mutations. The study found just over 10, 000 mutations in total, which together implicate almost 350 regions in the mouse genome in cancer formation.
Solving The Mystery Of Disease Origins: St. Louis Encephalitis
Before West Nile virus arrived in this country, we had (and still have) a home-grown relative of this pathogen. An epidemic of unknown origin exploded around St. Louis, Missouri in the autumn of 1933, a disease that is now known to be transmitted by mosquitoes from birds to people.
Researcher Finds An SOS Response To Cancer Causing Agents
University of Saskatchewan microbiologist Wei Xiao has found a way to trigger a protein combination called 9-1-1 that sends an SOS signal for cells to fight cancer-causing agents such as industrial toxins, ultraviolet radiation, and X-rays.The finding published this week in the prestigious journal Cell is seen as a breakthrough in cancer research that could lead to better cancer diagnosis through targeting defective genes.