Astrazeneca Stops Cholesterol Drug Trial Because Of Promising Results
Pharmaceutical giant AstraZeneca announced yesterday, Monday 31st March, it was stopping the JUPITER clinical trial on its cholesterol-busting drug Crestor (rosuvastatin calcium) because early findings showed that the drug reduced deaths and risk of heart problems in patients compared to placebo.
Trans Fat: Why It's Time To Eliminate This Dietary Villain
Trans fats are a cholesterol double whammy. Also known as trans fatty acids, trans fats raise low-density lipoprotein (LDL or "bad") cholesterol and lower high-density lipoprotein (HDL or "good") cholesterol.Experts consider trans fat the worst type of dietary fat.
Levitra reg; Therapy Suitable For Men With High Cholesterol
At the 23rd Annual European Association of Urology (EAU) Congress, results were presented which added evidence that Levitra (vardenafil HCI) works very well in men with dyslipidemia.(1) The double-blind, placebo-controlled trial in about 400 men showed that Levitra significantly improved the ability of men with erectile dysfunction (ED) and high cholesterol, to achieve and maintain an erection for successful sexual intercourse.
Pieces Coming Together In Parkinson's, Cholesterol Puzzle
In 2006, University of North Carolina at Chapel Hill researchers published a study that found people with low levels of LDL cholesterol are more likely to have Parkinson's disease than people with high LDL levels.But that study could not answer the question of whether low LDL (low-density lipoprotein) levels were present in study participants before they were diagnosed with Parkinson's, or if they developed low LDL levels after being diagnosed.
Lower Blood Pressure Linked To Statins
An article published in the Archives of Internal Medicinereports that statins - medications that are usually prescribed to lowerblood cholesterol levels - may also lower blood pressure. Beatrice A.Golomb, M.D., Ph.D., (University of California, San Diego, La Jolla)and colleagues noted a modest but significant reduction in bloodpressure for patients taking statins.
Two Merck Medicines Recommended For Approval In The European Union
Merck & Co., Inc. announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has recommended two medicines for marketing approval in the European Union (EU). The CHMP recommended marketing approval for TREDAPTIVE™
FDA Provides Clarity To Isis Regarding The Development Path For Mipomersen
Isis Pharmaceuticals, Inc. (Nasdaq: ISIS) and Genzyme Corp. (Nasdaq: GENZ) announced that the FDA has provided guidance regarding approval requirements for mipomersen. The FDA has indicated that reduction of LDL-cholesterol is an acceptable surrogate endpoint for accelerated approval of mipomersen for use in patients with homozygous familial hypercholesterolemia (hoFH).
CocoaVia Dark Chocolate Bars Shown To Lower Cholesterol
The results of a University of Illinois study have demonstrated an effective way to lower cholesterol levels - by eating chocolate bars."Eating two CocoaVia dark chocolate bars a day not only lowered cholesterol, it had the unexpected effect of also lowering systolic blood pressure, " said John Erdman, a U.
Physicians And Patients Nationwide Discuss Controversial Results Of Recent Cholesterol Lowering Study
Sermo (http://www.sermo.com), the largest physician-only online community, today announced the results of a physician survey prompted by the swirl of media coverage following the release of ENHANCE trial data at the recent American College of Cardiology (ACC) conference.
Sorting Of CEA Modulated By Cholesterol, Implications For Inflammatory Bowel Disease
In polarized Caco-2 cells, cholesterol was depleted by a combination of synthesis inhibition and plasma membrane extraction with complexing agents. This led to an increased sorting of CEA to the basolateral surface. Interestingly, polarity was not significantly affected by this approach.