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Obesity, Inactivity As Common Among Cancer Survivors As Rest Of Canadians

New research supported by the Canadian Cancer Society shows that many cancer survivors in Canada are overweight and inactive, which could put them at risk for health problems, including their cancer returning."These findings tell us that we need to look at ways to better support cancer survivors to become more active and to maintain a healthy body weight, " says Dr.

Melanoma Lurks In Larger Skin Lesions

Skin lesions that are about the size of a pencil eraser are more likely to be melanomas, a deadly form of skin cancer, than smaller moles, according to a new study led by NYU Langone Medical Center researchers.In a new study published in the April issue of Archives of Dermatology, the NYU researchers confirm that an important warning sign of melanoma moles that are larger than 6 millimeters, the size of a pencil eraser is still valid.

Risk Of Second Cancers Greatest In Younger Patients Treated For Non-Hodgkins Lymphoma

For survivors of non-Hodgkin's lymphoma the risk of developing subsequent secondary cancers is greater the younger the patient's age at diagnosis, concludes a study published in the Journal of Clinical Oncology. The study also showed that the toll of subsequent solid tumours was largest 21 to 30 years after diagnosis.

VioQuest Pharmaceuticals' Novel Akt Inhibitor VQD-002 Is Synergistic With Various Cancer Therapies In Preclinical Studies

VioQuest Pharmaceuticals (OTCBB: VQPH) announced preclinical data demonstrating that the company's novel AKT inhibitor VQD-002 delivers synergistic benefit in combination with a range of cancer therapies including trastuzumab (Herceptin; Genentech, Roche), dasatinib (Sprycel;

UF Researchers Identify Key Target For Cancer Therapies

New therapies must target a key protein interaction to destroy aggressive cancer cells' protective force field, University of Florida scientists reported this week at the American Association for Cancer Research's annual meeting in San Diego. The barrier deflects damage from radiation or chemotherapy, making some cancer cells difficult to destroy, but researchers from UF and the University of North Carolina at Chapel Hill may have discovered why.

New Data Demonstrate That Lapatinib Decreases Tumourigenic Breast Cancer Stem Cells In Women Receiving Neoadjuvant Treatment

GlaxoSmithKline today announced for the first time final results from a prospective study that demonstrated that lapatinib decreases tumourigenic ('cancer initiating') stem cells in primary breast cancers of women receiving neoadjuvant treatment.[i] These data were highlighted in an oral presentation at the 6th European Breast Cancer Conference (EBCC-6).

Ovarian Cancer Stem Cells Identified, Characterized And Cloned, Leading To More Effective Treatment

Researchers at Yale School of Medicine have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its resistance to chemotherapy. "These results bring us closer to more effective and targeted treatment for epithelial ovarian cancer, one of the most lethal forms of cancer, " said.

How New Technologies Could Help Doctors Predict Patient Outcomes

As potential cancer therapies proliferate, researchers and clinicians are striving to measure their effectiveness and to more accurately predict which patients will receive the most benefit. At the American Association for Cancer Research 2008 Annual Meeting, April 12-16, 2008, researchers presented data on a new role for MRI in brain cancer, how doctors can more effectively measure response to commonly used cancer drugs, and a unique method for predicting the risk of breast cancer spread.

Identification And Characterization Of Cancer Stem Cells In Ovarian Cancer

Researchers have identified stem cells in epithelial ovarian cancer that may play a role in the cancer's resistance to chemotherapy. The findings hold potential for more effective targeting of one of the most lethal forms of cancer. "Present chemotherapy modalities eliminate the bulk of the tumor but leave a core of these cancer stem cells with high capacity for repair and renewal, " said Gil Mor, M.

Prospective Identification, Tracking And Targeting Of Cancer-initiating Cells In Breast Cancer And Glioma Via Low Proteosome Activity

Identification of cancer stem cells remains a challenge at the microscopic level, but researchers have concluded that low proteosome activity can be an effective marker to isolate these cells from the wider population and track their response to treatment in vitro and in vivo.

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