Mortality During Sepsis Reduced By Ashwell Receptor
In research that solves the longest-standing mystery in glycobiology - a field that studies complex sugar chains called glycans - researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is critical in helping the body fight off the abnormal and lethal blood clotting caused by bacterial infection.
Making A Fist Of Blood Taking - And Ending Up In Casualty
A paper in the latest issue of the Annals of Clinical Biochemistry shows how the manner in which blood is collected from patients for some blood tests alters the results of those tests when it comes to analysis. Clenching the fist during blood taking could land some patients in their nearest A&E department being monitored for a heart emergency.
Modification of Blood-Clotting Protein For People With Hard-To-Treat Hemophilia
Pathologists at The University of Texas Health Science Center at Houston have developed a chemically modified protein that may help people with a hard-to-treat form of a genetic bleeding disorder known as Hemophilia A. The discovery and the results of pre-clinical tests appear in the May 2 issue of the Journal of Biological Chemistry.
Sanofi-aventis Withdraws Its Marketing Authorisation Application ForAquilda satavaptan , Europe
The European Medicines Agency (EMEA) has been formally notified by Sanofi-Aventis of its decision to withdraw the application for a centralised marketing authorisation for the medicine Aquilda (satavaptan) 5 and 25 mg film-coated tablets. Aquilda was intended to be used for the treatment of euvolaemic and hypervolaemic dilutional hyponatraemia, a metabolic condition in which the body's blood sodium level falls below normal.
ZymoGenetics Announces FDA Approval Of RECOTHROMTM 20,000-IU Vial Size And Co-Packaging With Spray Kit
ZymoGenetics, Inc. (NASDAQ:ZGEN) announced that the United States Food and Drug Administration (FDA) has approved a Prior Approval Supplement application for a 20, 000 international unit (IU) vial of RECOTHROMTM Thrombin, topical (Recombinant) and also approved co-packaging of the 20, 000-IU vial with the ZymoGenetics Spray Applicator Kit.
Manufacturer Removes Remaining Stocks Of Trasylol
Background: On Nov. 5, 2007, the U.S. Food and Drug Administration announced that Bayer Pharmaceuticals Corp. agreed to an FDA-requested marketing suspension of Trasylol, a drug used to control bleeding during heart surgery. At that time, preliminary results from a Canadian study suggested an increased risk for death compared to two other drugs used to control bleeding.
Avoiding Spleen Removal For Cooley's Anemia Sufferers
Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100, 000 African-Americans.
Biovitrum And Syntonix Dose First Hemophilia B Patient In Clinical Trial Of A Novel Factor IXFc Treatment
Biovitrum AB (STO: BVT) and Syntonix Pharmaceuticals, Inc., a subsidiary of Biogen/Idec (NASDAQ: BIIB) announced the initiation of a phase I/IIa open-label, dose escalation study of a long-acting, recombinant Factor IXFc (FIXFc) protein in patients with hemophilia B.
New Method Identifies Rat Poison In Humans
Researchers at the Norwegian Institute of Public Health (NIPH) have developed a method to identify bromadiolone poisoning in humans. Bromadiolone is a rat poison that can be purchased freely in shops. A number of cases have been reported internationally where people have been poisoned, with a mortality rate of 20 percent.
Don't Sit Still And Avoid DVT
"Desk-bound workers at double DVT risk, " reads the headline in The Daily Telegraph. Workers who "sit at a desk for eight hours a day and spend more than three hours without stretching double their risk of developing deep vein thrombosis (DVT)", the newspaper says.