Vaccine Triggers Immune Response, Prevents Alzheimer's
A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer's disease-like pathology in mice without causing inflammation or significant side effects.Vaccinated mice generated an immune response to the protein known as amyloid-beta peptide, which accumulates in what are called "amyloid plaques" in brains of people with Alzheimer's.
Study Outlines Misconceptions About Alzheimers, Australia
Better targeted education is needed to prevent misconceptions held by the general public about Alzheimer's disease, according to Queensland University of Technology researcher Dr Karen Sullivan. Registered psychologist and senior lecturer for the School of Psychology and Counselling in the Faculty of Health, Dr Sullivan has been studying people's misconceptions about the condition for the past five years, and said there were a number of things which people misunderstood about it.
Alzheimer's Disease: Finding Has Implications For Host Of Neurodegenerative Diseases
Researchers from the University of Pennsylvania School of Medicine have shown, in unprecedented detail, how a small molecule is able to selectively take apart abnormally folded protein fibers connected to Alzheimer's disease and prion diseases. The findings appeared online in the Proceedings of the National Academy of Sciences. Finding a way to dismantle misfolded proteins has implications for new treatments for a host of neurodegenerative diseases.
Study Identifies New Gene For Late-Onset Alzheimer's Disease - Findings Lead To New Line Of Investigation Into Alzheimer's Research
A new study has identified the cause of late-onset Alzheimer's disease in several large families in which many siblings suffer from the disease. The gene, known as TRPC4AP on chromosome 20, is involved with calcium regulation. It is known that when calcium levels are not carefully controlled, cells can die, leading to the onset of disease. Alzheimer's disease is a complex progressive neurodegenerative disorder in which patients suffer from profound cognitive decline.
Ibuprofen, Aspirin, Naproxen May Be Equally Effective At Reducing Risk Of Alzheimer's Disease
Different types of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen, and aspirin, appear to be equally effective in lowering the risk of Alzheimer's disease, according to the largest study of its kind published in the May 28, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.
Antipsychotics Triple Risk Of Hospitalisation For People With Dementia, UK
Alzheimer's Society comment on new research showing that short term use of antipsychotic drugs more than triple the risk of a serious event causing hospitalisation or death in people with dementia living in the community.This comprehensive study highlights the life-threatening effects antipsychotics have on people with dementia and reveals that people in the community are at greater risk than those in nursing homes.
Sandra Day O'connor, Newt Gingrich Testify At Aging Hearing On Alzheimer's, USA
U.S. Senate Special Committee on Aging Chairman Herb Kohl (D-WI) held a hearing on Alzheimer's, a disease that currently affects over five million Americans and their families. Witnesses provided an update on the latest research and treatments, issues surrounding early-onset diagnoses, the importance of training and support for patient caregivers, and the need for a comprehensive strategy as more and more Americans are diagnosed with the disease.
First Conclusive Evidence Of Alzheimer's-Like Brain Tangles In Nonhuman Primates, Findings Could Pave Way For New Human Treatments
Researchers at the Yerkes National Primate Research Center, Emory University, have discovered the first conclusive evidence of Alzheimer's-like neurofibrillary brain tangles in an aged nonhuman primate.
Likely Causative Gene For Late-Onset Alzheimer's Discovered
The genetic profile of two large Georgia families with high rates of late-onset Alzheimer's disease points to a gene that may cause the disease, researchers say.Genetic variations called single nucleotide polymorphisms, or SNPs, are common in DNA, but this pattern of SNPs shows up in nine out of 10 affected family members, says Dr. Shirley E.
Applied NeuroSolutions To Offer P-Tau 231 Test For Use In Alzheimer's Disease Clinical Trials
Applied NeuroSolutions, Inc. (OTC BB:APNS)( http://www.AppliedNeuroSolutions.com), a company focused on the development of products for the early diagnosis and treatment of Alzheimer's disease ("AD"), today announced an initiative to provide its P-Tau 231 cerebrospinal fluid (CSF) test to companies undertaking AD clinical trials.