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Mitochondria Play Role In Pathogenesis Of Alzheimer's Disease And Estrogen-Induced Neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease. Now, a new study from the laboratory of Dr.

Alzheimer's Society Comment On Award For Ground-Breaking Dementia Documentary

We are thrilled to hear Malcolm & Barbara: Love's Farewell has been named best single documentary at the 34th Broadcasting Press Guild Television and Radio Awards. When Malcolm Pointon was diagnosed with Alzheimer's disease, he and his wife Barbara made the decision to allow a camera to follow them up until the final stages of the disease, which eventually killed him.

Redox-Active Iron Is A Sensor Of Cognitive Impairment Associated With Alzheimer's Disease

An innovative discovery has been reported that highlights the problems that oxidative stress resulting from iron cumulated in the human brain can generate in relation with the pathogenesis of Alzheimer's disease (AD), the brain disorder affecting almost 30 million throughout the world.

New Technologies Help Determine Whether Cognitive Impairment Will Lead To Alzheimer's

With nearly 10 million baby boomers at risk for developing Alzheimer's disease, researchers are taking a closer look at a condition known as mild cognitive impairment. This is a state between the normal forgetfulness that comes with aging and the more pronounced thinking deficits of dementia.

Alzheimer's Patients Currently Being Enrolled For Phase III Eli Lilly Study

Eli Lilly and Co has started a Phase III Clinical Trial of LY450139, an investigational gamma secretase inhibitor for the treatment of patients with mild/moderate Alzheimer's disease. The trial aims to see whether it can slow the progression associated with Alzheimer's by inhibiting gamma-secretase.

EPIX Pharmaceuticals To Present Phase 2a Alzheimer's Data At Keystone Symposia

EPIX Pharmaceuticals, Inc. (NASDAQ:EPIX), a biopharmaceutical company focused on discovering and developing novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform, announced that Tom Megerian, M.

Large Bellies Indicate Double Or Triple The Risk Of Dementia

People in their 40s with larger stomachs have a higher risk for dementia when they reach their 70s, according to a study published in the March 26, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.Previous studies have looked at central obesity (as determined by waist circumference) and body mass index in the elderly and its link to dementia risk.

Dementia Risk In Old Age Linked To Belly Size In Midlife

A new study by researchers from the US and Sweden showed that having a large belly in midlife increased the risk of having dementia in old age, with overweight and obese people with large bellies having double or triple the risk. In other words, while being overweight and obese was a risk factor, the study showed this was significantly affected by where the weight was carried in midlife.

Alzheimer's Society Comment On Bafta Nomination For Dementia Documentary, UK

It is fantastic that Malcolm & Barbara: Love's Farewell has been nominated for a Bafta Television award in the category of best single documentary.It is another important step toward bringing dementia out of the shadows and leading the fight against this devastating condition.

Alzheimer's Society Comment On Care Homes, The Human Rights Act And Department Of Health Announcement On Elder Abuse Research, UK

Two thirds of the country's care home residents are living with dementia. This hat-trick of announcements will play an important part in tackling the abuse and neglect of people with this devastating condition and help ensure failing homes are forced to improve standards.

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