Major depression and coronary artery disease are only modestly related throughout an individual's lifetime, but studying how the two interact over time and in twin pairs paints a more complex picture of the associations between the conditions, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals. For example, the association between coronary artery disease onset and major depression risk is much stronger over time than vice versa. "While an association between major depression and coronary artery disease has long been noted and recently confirmed, the direction and cause of this association remain unclear, " the authors write as background information in the article.
A New Plug For The Hole In The Heart: New Procedure May Help Save Lives Of Those Affected By Common Congenital Heart Defect
Heart specialists at St. Joseph Hospital in Orange, Calif. have performed a new procedure in which they repaired a hole in the patient's heart through a tiny incision, offering the patient a much safer alternative verses open heart surgery. The condition, called ventricular septal defect (VSD), is a common heart birth defect, accounting for about 30% of all heart defects according to the Adult Congenital Heart Association. The condition leaves a hole in the heart, affecting blood flow and can be potentially life threatening. "Before the surgery, I was experiencing more fatigue than before and my cardiologist knew that something had to be done, and fast, " said Yvonne Domingos, a San Diego resident who recently underwent the VSD closure procedure at St.
Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart. In the study, the heart of mice lacking Sirt3 was found to show signs of becoming enlarged (a process known as cardiac hypertrophy), at about 8 weeks of age. Further, these mice responded dramatically to conditions that induce cardiac hypertrophy, whereas mice overexpressing Sirt3 were protected from cardiac hypertrophy under the same conditions.
Emergency physicians should trust their judgment when evaluating patients who report with chest pain symptoms, said a group of researchers led by Abhinav Chandra, M.D., at Duke University Medical Center. Their research suggests that emergency physicians should counsel with other physicians against discharge when they feel strongly about a patient for whom there is no compelling data, other than our evaluation and judgment, Chandra said. "There is evidence for emergency room physicians to trust their gut instinct when they have to make a quick decision about a potential heart patient, before lab results are even returned, " said Chandra, director of acute care research and of the clinical evaluation unit in the Duke Division of Emergency Medicine.
Doctors To Use 'Trained' Stem Cells To Heal Heart - During Heart Attack, Doctors Inject 'Trained' Stem Cells To Minimize Damage
After suffering two heart attacks and undergoing two surgeries, Bob Chirico does what he can to keep his heart strong - making it a point to exercise every day. "I get about four miles on the bike. And I get off the bike and I don't really have any problems. I have no angina, no shortness of breath, " says Bob. But for Bob and millions of people who survive heart attacks, the damage is already done. Once you lose heart muscle, it's gone for good. But scientists at Ohio State University Medical Center are working to change that. In lab tests, they're injecting stem cells from adult bone marrow into areas of the heart that have lost blood supply, to try and get the heart to heal itself.
UPMC Cardiologist Named Master Clinician Chair In Cardiovascular Medicine At UPMC Cardiovascular Institute
William P. Follansbee, M.D., professor of medicine and radiology at the University of Pittsburgh School of Medicine and director of Nuclear Cardiology at the UPMC Cardiovascular Institute, has been selected the inaugural Master Clinician Chair in Cardiovascular Medicine at the UPMC Cardiovascular Institute. Named in his honor, the William P. Follansbee, M.D., Master Clinician Chair in Cardiovascular Medicine was established to recognize a faculty member who is both an outstanding academic clinician and educator. This chair allows the recipient to support the training of tomorrow's physicians, teaching them to apply scientifically advanced treatments while preserving the traditions of bedside care.