New research claims that rosiglitazone, a drug used to treat Type 2 diabetes, is associated with an increased risk of heart failure and death among older people compared to a similar drug called pioglitazone. Researchers in Canada compared the risk of heart attack, heart failure and death in people treated with rosiglitazone and pioglitazone. They identified nearly 40, 000 people aged 66 years and older who started treatment with either rosiglitazone or pioglitazone between April 2002 and March 2008. Confirmation of previous studies Dr Iain Frame, Director of Research at Diabetes UK, said: "This is a well-designed retrospective study of older people with Type 2 diabetes using rosiglitazone or pioglitazone.
Health-conscious people know that high levels of total cholesterol and LDL cholesterol (the so-called "bad" cholesterol) can increase the risk of heart attacks. Now scientists are reporting that another form of cholesterol called oxycholesterol - virtually unknown to the public - may be the most serious cardiovascular health threat of all. Scientists from China presented one of the first studies on the cholesterol-boosting effects of oxycholesterol t the 238th National Meeting of the American Chemical Society. The researchers hope their findings raise public awareness about oxycholesterol, including foods with the highest levels of the substance and other foods that can combat oxycholesterol's effects.
As children and teens begin school again, they are more susceptible to the pain and discomfort of headaches and migraines. The change in schedule, new teachers, new friends and schoolwork can increase stress and consequently, increase headaches. Doctors at Nationwide Children's Hospital say there are some steps parents can take to help prevent the onset of their headaches during this hectic time of year. More than a third of children suffer from recurrent headaches headaches that occur more than once a month. Most are tension headaches, which are less severe and do not occur with nausea or vomiting. Migraines, which account for approximately 25 percent of headaches, are much more disruptive and frequently occur within families due to a genetic component.
Researchers from North Carolina State University and Mayo Clinic have developed a computer model that medical doctors can use to determine the best time to begin using statin therapy in diabetes patients to help prevent heart disease and stroke. "The research is significant because patients with diabetes are at high risk for cardiovascular disease and statins are the single most commonly used treatment for patients at risk of heart disease and/or stroke, " says Dr. Brian Denton, "and this model can help determine the best course of action for individual patients based on their risk of developing cardiovascular disease." Denton is an assistant professor in NC State's Edward P.
Patients With Non-Valvular Atrial Fibrillation At Risk Of Stroke Could Have An Alternative To Long Term Warfarin Therapy
An article published in this week's edition of The Lancet reports that patients with atrial fibrillation at risk of stroke could be offered percutaneous closure of the left atrial appendage instead of long-term warfarin therapy. The findings are from the PROTECT AF study. The article is the work of Professor David R Holmes, Mayo Clinic, Rochester, MN, USA, and collaborators. Atrial fibrillation is irregular heartbeat and the most frequent sustained cardiac arrhythmia. As the world's population ages, its occurrence is expected to increase. Atrial fibrillation causes the upper chambers of the heart to tremble. This can cause blood to pool and form blood clots in an area of the heart called the left atrial appendage (LAA).
In a first-of-its kind study, scientists reported at the 238th National Meeting of the American Chemical Society (ACS) that snack foods like popcorn and many popular breakfast cereals contain "surprisingly large" amounts of healthful antioxidant substances called "polyphenols." Polyphenols are a major reason why fruits and vegetables - and foods like chocolate, wine, coffee, and tea - have become renowned for their potential role in reducing the risk of heart disease, cancer, and other diseases. Until now, however, no one knew that commercial hot and cold whole grain cereals - regarded as healthful for their fiber content - and snack foods also were a source of polyphenols.