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Clinical Data, Inc. Initiates Phase III Trial Of Stedivaze For Cardiac Stress Testing

Clinical Data, Inc. (NASDAQ: CLDA) announced that it has enrolled the first patient in its initial Phase III trial of Stedivaze™ , a potential best-in-class vasodilator for use in cardiac stress testing. The study will evaluate the safety and efficacy of Stedivaze (apadenoson) for use as a pharmacologic stress agent in myocardial perfusion imaging (MPI), a method for detecting defects in the blood supply to the heart. The Phase III trial will also compare the tolerability of Stedivaze to adenosine, a standard pharmacologic stress agent used in MPI scans. "The superior selectivity and pharmacokinetic profile of Stedivaze support its potential for improved tolerability compared to adenosine, as seen in Phase II studies, " said Carol R.

Inhaling A Heart Attack: How Air Pollution Can Cause Heart Disease

It's well known that measures such as exercise, a healthy diet and not smoking can help reduce high blood pressure, but researchers at the University of Michigan Health System have determined the very air we breathe can be an invisible catalyst to heart disease. Inhaling air pollution over just two hours caused a significant increase in diastolic blood pressure, the lower number on blood pressure readings, according to new U-M research. The study findings appear in the current issue of Hypertension, a publication of the American Heart Association. Nearly one in three Americans suffer from hypertension, a significant health problem that can lead to heart attack, heart failure, stroke, and other life-threatening problems.

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Athletes Should Be Screened For Heart Abnormalities To Prevent Sudden Death

Young athletes should be routinely tested for heart abnormalities to prevent sudden cardiac death that is triggered by vigorous exercise, using a simple protocol, which includes a heart trace (electrocardiogram or ECG). This is the conclusion of several studies in the first of a series of quarterly partnership issues between the British Journal of Sports Medicine and the International Olympic Committee (IOC), which are dedicated to injury prevention in elite sports. Sudden cardiac death is the leading cause of death in young athletes, but exactly how common it is, is unknown as figures vary considerably and there is no mandatory reporting.

American University Of Beirut Medical Team Successfully Performs First Artificial Heart Implant In Lebanon

A medical team at the American University of Beirut Medical Center (AUBMC) has successfully performed the first artificial heart implant in Lebanon, saving the life of a 37-year-old man suffering from terminal heart failure. Led by two AUB doctors, the six-hour operation, which took place on August 28, 2009, was deemed a success after the patient survived the first critical 72 hours and showed improvements in all his vital signs. The artificial heart implant operation involves the insertion of a left ventricular assist device (LVAD) that assumes the functions of the left ventricle of the heart, the dominant chamber which is responsible for pumping oxygenated blood via the aorta to the rest of the body.

Important Nutritional Recommendations Not Being Met By People With Type 2 Diabetes

People with type 2 diabetes are not consuming sufficiently healthy diets and could benefit from ongoing nutritional education and counseling, according to a new study by researchers at Wake Forest University School of Medicine and colleagues. The study appears in the August issue of the Journal of the American Dietetic Association. "The most important thing about controlling diabetes, especially type 2 diabetes, is being able to manage energy in and energy out, and the best way to do that is through the diet, " said Mara Z. Vitolins, Dr.P.H., M.P.H., R.D., lead author on the study and an associate professor in the department of epidemiology and prevention, part of the School of Medicine's Division of Public Health Sciences.

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Pennsylvania Cardiology Program Implanting Defibrillators That Slow Heart Failure Progression

Electrophysiologists Robert Stevenson, MD, and Jeffrey L. Williams, MD, MS, FACC, are safely implanting cardiac resynchronization therapy defibrillators in the Good Samaritan Hospital (GSH) Cardiology (Heart Failure) Program. These advanced defibrillators are used to treat sudden cardiac death, which is abrupt heart failure, usually due to an electrical rhythm dysfunction in the lower chambers of the heart that causes the heart to pump blood ineffectively. In addition, these devices have an additional implanted pacing lead that helps to resynchronize an abnormally pumping heart in an attempt to lessen heart failure symptoms for cardiology patients.

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