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New Immune Link To Inflammation Scarring In Graves' Disease

A cell type that causes significant scarring in lung disease appears to have a similar effect in Graves' disease, University of Michigan Health System researchers have found. The cells, called fibrocytes, are present at a higher than normal frequency in patients with Graves' disease, according to a new study, the first to associate fibrocytes with this autoimmune disease. The discovery is a major step forward in explaining how and why the orbit of the eye is subject to scarring and inflammation in Graves' disease. The findings may also lead to new treatment strategies to target scarring or fibrosis, say authors Raymond Douglas, M.D., Ph.

What Is Thyroid Cancer? What Causes Thyroid Cancer?

Thyroid cancer is a type of cancer that occurs in the cells of the thyroid. The thyroid is a butterfly-shaped gland located at the base of the neck. It produces hormones that regulate the heart rate, blood pressure, body temperature and weight. Thyroid cancer is not common. However, thyroid cancer rates seem to be increasing. This may be the result of improvements in technology making it easier to detect the condition at an earlier stage. This allows the finding of small thyroid cancers that may not have been found previously. Women are more likely to get thyroid cancer than men. The thyroid gland The main role of the thyroid gland is to release hormones, which are powerful messenger chemicals that have an important effect on the functions of the body.

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Prevalence Of Thyroid Cancer Rises Sharply

As seen on "NBC Nightly News" Monday, December 21, the thyroid cancer rate is rising rapidly, especially among women. The American Thyroid Association's members are working to educate more people about thyroid cancer as well as treat and cure it. Facts on prevalence and impact of thyroid disease. -- Nearly 20 million Americans have some form of thyroid disease. -- About 60 percent of those with thyroid disease are unaware of their condition. -- Women are five to eight times more likely than men to have thyroid problems. -- One woman in eight will develop a thyroid disorder during her lifetime. -- Most thyroid cancers respond to treatment, although a small percentage can be very aggressive.

Growing Evidence Suggests Progesterone Should Be Considered A Treatment Option For Traumatic Brain Injuries

Researchers at Emory University in Atlanta, GA, recommend that progesterone (PROG), a naturally occurring hormone found in both males and females that can protect damaged cells in the central and peripheral nervous systems, be considered a viable treatment option for traumatic brain injuries, according to a clinical perspective published in the January issue of the American Journal of Roentgenology. "Traumatic brain injury (TBI) is an important clinical problem in the United States and around the world, " said Donald G. Stein, PhD, lead author of the paper. "TBI has received more attention recently because of its high incidence among combat casualties in Iraq and Afghanistan.

HIV-Infected Postmenopausal Women At High Risk For Bone Fractures

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), postmenopausal HIV-infected women have a high prevalence of low bone mineral density and high bone turnover placing them at high risk for future bone fractures. "As HIV-infected individuals live longer with potent antiretroviral therapy (ART), metabolic complications such as low bone density and osteoporosis are increasingly recognized, " said Michael Yin, MD of Columbia University Medical Center in New York and lead author of the study. "Although numbers of HIV-infected postmenopausal women are increasing and postmenopausal women are at highest risk for osteoporotic fractures, few studies have evaluated skeletal status in this group.

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New Human Reproductive Hormone Could Lead To Novel Contraceptives And New Cancer Treatments

Nearly 10 years after the discovery that birds make a hormone that suppresses reproduction, University of California, Berkeley, neuroscientists have established that humans make it too, opening the door to development of a new class of contraceptive and possible treatments for cancer or other diseases. The hormone, gonadotropin inhibitory hormone (GnIH), has the opposite effect from gonadotropin releasing hormone, a key reproductive hormone. While GnRH triggers a cascade of hormones that prime the body for sex and procreation, GnIH puts a brake on the cascade. "Identifying the inhibitory hormone in humans forces us to revise our understanding of the control mechanism of human reproduction, " said first author Takayoshi Ubuka, a post-doctoral fellow in the UC Berkeley Department of Integrative Biology and in the Helen Wills Neuroscience Institute.

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