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Link Between Symptoms Of Depression In Obese Children And Elevated Cortisol

A new study connects abnormalities of the "stress" hormone cortisol with symptoms of depression in obese children, and confirms that obesity and depression often occur together, even in children. The results were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C. "There is evidence in adults that abnormal regulation of cortisol plays a role in both obesity and depression, " said the study's lead author, Panagiota Pervanidou, MD, of Athens University Medical School in Athens, Greece. "Our study indicates that cortisol abnormalities may underlie obesity and depression starting in childhood." Cortisol is a steroid hormone that helps the body respond to stress but also has other functions, including converting fat, protein and carbohydrates into energy.

Important Therapeutic Target For Breast Cancer: Newly Appreciated Membrane Estrogen Receptor

New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that linked the transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is exciting about this new work, " says Filardo, "is that it provides some insight into the influence of GPR30 at the cellular level.

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What Is Menstruation? What Are Periods?

A period, or menstruation, is the shedding of the endometrium - the uterine lining. Menstruation is also known as menses. All female humans, as well as some other female mammals, have regular periods during their reproductive age. Menstruation which includes bleeding from the vagina is found mainly among humans and similar animals, such as primates. In many mammals, the endometrium is reabsorbed by the animal. As far as humans are concerned a period is a bleed from the womb (uterus) that is released through the vagina. Women have a period every 28 days approximately. However, some women may have a 24-day cycle while other may have a 35-day one.

Hope For Treatment Of The Metabolic Syndrome Offered By Natural Hormone

Angiotensin 1-7, a hormone in the body that has cardiovascular benefits, improves the metabolic syndrome in rats, according to a new study. The results were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C. "No specific form of medical therapy for the metabolic syndrome presently exists, " said the study's lead author, Yonit Marcus, MD, a PhD student at the Weizmann Institute of Science in Rehovot, Israel. "But an estimated 20 to 25 percent of the world's adult population has the metabolic syndrome." The metabolic syndrome is a cluster of risk factors that raise the risk of developing heart disease, stroke and diabetes.

What Are Electrolytes?

An electrolyte is "any compound that, in solution or in molten form, conducts electricity and is decomposed (electrolyzed) by it. It is an ionizable substance in solution" (Medilexicon's medical dictionary ). An electrolyte is any substance that contains free ions that behaves as an electrically conductive medium (conducts electricity). All higher forms of life cannot exist without electrolytes, and that includes humans. In our bodies, electrolytes include sodium (Na + ), potassium (K + ), calcium (Ca 2+ ), bicarbonate (HCO 3 -, magnesium (Mg 2+ ), chloride (C1 - ), hydrogen phosphate (HPO 4 2- ), and hydrogen carbonate (HCO 3 - ).

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Could Estrogen Improve Outcomes After Traumatic Brain Injury, Shock?

UT Southwestern Medical Center researchers are conducting two pilot clinical trials to determine whether a single, early dose of estrogen can improve survival and neurological outcomes after severe traumatic brain injury or traumatic hemorrhagic shock. In these double-blind studies, male patients transported to Parkland Memorial Hospital following severe traumatic brain injury or severe blood loss associated with a traumatic injury will be assigned randomly to receive either Premarin (estrogen) or a placebo intravenously after arriving in the emergency department. Estrogen or a placebo will be administered as a single-dose within two hours of injury.

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