Study Finds Association Between Genes That Regulate Maternal Inflammatory Response, Bacterial Vaginosis And Preterm Delivery
In a study presented at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting™ in Chicago, researchers showed the use of haplotype tagging (hap-tag) single-nucleotide polymorphisms (SNPs) to study the relationship between genetic predispositions, an environmental factor - bacterial vaginosis, and preterm birth. Studies previously demonstrated that genetic variation within genes that regulate the maternal inflammatory response are associated with an increased risk of spontaneous preterm delivery (SPTD). The new study sought to determine if an environmental exposure associated with maternal inflammation, bacterial vaginosis (BV), modifies these genetic susceptibilities.
New research shows that two different antimicrobial regimens for treating buruli ulcer (Mycobacterium ulcerans infection) are effective at treating early, limited disease. This is the conclusion of an Article published Online First (http://www.thelancet.com) and in an upcoming edition of The Lancet -written by Professor Tjip S van der Werf, University Medical Centre Groningen, Netherlands, and colleagues. Buruli ulcer is classed a neglected tropical disease. The early stage of infection is characterised by a painless nodule, with lesions developing on the skin, and occasionally in adjacent bone, as the disease progresses. Surgery was the standard treatment for Buruli ulcer disease until WHO issued provisional guidelines in 2004 recommending treatment with antimicrobial drugs (streptomycin and rifampicin) in addition to surgery.
A new virology textbook published by ASM Press educates the reader by focusing on the families. Based on the author's experiences teaching virology for more than 35 years, Virology: Molecular Biology and Pathogenesis enables readers to develop a deep understanding of fundamental virology by emphasizing principles and discussing viruses in the context of virus families. "Virology: Molecular Biology and Pathogenesis is meant to be used as a textbook for a comprehensive virology course aimed at advanced undergraduate and graduate students. It was conceived and organized to express my avid belief that the best way to teach virology is to discuss viruses in the context of virus families, " says author Leonard Norkin of the University of Massachusetts, Amherst.
The Food and Drug Administration, along with the Centers for Disease Control and Prevention and the U.S. Department of Agriculture's Food Safety and Inspection Service, continues to work closely with the Rhode Island Department of Health and other states in the investigation of an outbreak of Salmonella Montevideo infections associated with certain Italian-style sausage products including salami/salame. The CDC reports that 207 people have been infected with a matching strain of Salmonella Montevideo in at least 42 states and the District of Columbia. Recently, the CDC and public health officials in multiple states conducted an epidemiologic study by comparing foods eaten by 41 ill and 41 well persons.
"PKD" stands for polycystic kidney disease characterized by the formation of multiple cysts on kidney surface causes increase in its size and weight. The weight of cyst filled kidney can reach 20-30 pounds. It is the most common heredity kidney disorder passes down through families. If both parents are carrier of this disease there is 50% chance for child to develop this disease but if one of the parents carries it the chance of its occurrence in child remains 25%. In this case child does not develop it but simply passes it to the next generation. Forms of Polycystic Kidney Disease This disease occurs in two forms; Autosomal dominant PKD and Autosomal recessive PKD.
U.N. Secretary-General Ban Ki-moon on Wednesday asked former President Bill Clinton, currently the U.N. special envoy for Haiti, to oversee aid and rebuilding efforts in Haiti, CNN reports (2/3). Ban "specifically asked President Clinton to assume a leadership role in coordinating international aid efforts from emergency response to the reconstruction of Haiti, " U.N. spokesperson Martin Nesirky said, Reuters reports. "There's an awful lot of goodwill out there, an unprecedented flow of aid and good intentions and cash, and the idea is to ensure that that comes together in the right way, " Nesirky said. In this role, Clinton will be charged with coordinating the work of NGOs, private groups, governments and U.