An independent large study conducted by MEDCO Health Solutions Inc. found that women treated with tamoxifen for breast cancer doubled the risk of the disease returning if they used antidepressants--in particular, Paxil and Prozac. The researchers used medical records to identify 353 women taking tamoxifen plus other drugs that might interfere with it, and 945 women taking tamoxifen alone. Those taking a drug combo did so for about a year on average. Next, researchers checked to see how many were treated for second cancers in the following two years. "Breast cancer recurred in about 7 percent of women on tamoxifen alone, and in 14 percent of women also taking the antidepressants Paxil and Prozac, and, to a lesser extent, Zoloft .
Benefit of bupropion proven - Benefit of reboxetine not proven: manufacturer conceals study data On 10 June 2009, the Institute for Quality and Efficiency in Health Care (IQWiG) presented the preliminary results of its benefit assessment of certain newer antidepressants. The project commissioned by the Federal Joint Committee (G-BA) is concerned with assessing the benefit of three agents, reboxetine, mirtazapine and bupropion XL in adult patients with depression, according to the German drug approval status. Interested parties and institutions may submit written comments on the preliminary report up until 9 July. Reboxetine: no proof of benefit The assessment produced different results for the three agents.
There is a frenzied push by mental health providers--almost all of whom have financial ties to psychotropic drug manufacturers--to persuade government to adopt a policy of screening teenagers and women for depression. The women being targeted at this juncture are vulnerable: they are either pregnant or have just given birth to a child. In both cases, both mother and infant are at risk of being harmed by pharmacological interventions. The problem with mental screening starts with the fact that the method for mental screening is an unreliable suggestive questionnaire which is noted for its high rate (84%) for misidentifying normal teens as having mental disorders.
Researchers trying to uncover why premature birth is a growing problem in the United States and one that disproportionately affects black women have found that pre-pregnancy depressive mood appears to be a risk factor in preterm birth among both blacks and whites. Black women, however, have nearly two times the odds of having a preterm birth compared to white women, according to Amelia Gavin, a University of Washington assistant professor of social work and lead author of a new study that appears online in the June issue of the Journal of Women's Health. "Preterm births are one of the most significant health disparities in the United States and the overall number of these births increased from 10.
Earlier parental-mandated bedtimes could help protect teens from depression and suicidal thoughts by lengthening sleep duration, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies. The study by James Gangwisch, PhD, of Columbia University in New York, examined data from 15, 659 adolescents. A total of 1, 143 teens (7.3 percent) suffered from depression and 2, 038 (13 percent) had suicidal thoughts. Adolescents with parental-mandated bedtimes at midnight or later were 25 percent more likely to suffer from depression and 20 percent more likely to have suicidal ideation compared with adolescents who had parental-mandated bedtimes of 10 p.
Depression is a major public health problem, and one of the most important challenges for psychiatrists is to determine whether an individual with depression should receive cognitive-behavioral therapy or treatment with antidepressant medication. A study by researchers from Emory University, presented at the Annual Meeting of the Organization for Human Brain Mapping in San Francisco, used brain imaging along with sophisticated statistical techniques to examine the differences in brain function that result from these two different kinds of treatment. Forty individuals with depression were scanned with magnetic resonance imaging after undergoing cognitive behavioral therapy or antidepressant therapy.