Osteoarthritis is one of the most common types of arthritis. It can either be degenerative, worsening over a period of time, or will stabilize at a certain point, usually when damage to the joints has already occurred. Although there is currently no cure, there are a number of osteoarthritis treatments available to reduce symptoms and alleviate pain. Painkillers may be prescribed to mask the pain caused by osteoarthritis. These can vary in strength, from over the counter medicines such as ibuprofen and aspirin to stronger medicines such as morphine, which must be prescribed by your doctor. Prescription medication for osteoarthritis includes Prescription Nonsteroidal Anti-Inflammatory Drugs (known as NSAIDs) and Corticosteroids.
In the new Swedish-Finnish study, published in Nature Genetics, the researchers identified five loci that predispose to an SLE-related disease in Nova Scotia duck tolling retrievers. The study indicates that the homogeneity of strong genetic risk factors within dog breeds make dogs an excellent model in which to identify pathways involved in human complex diseases. The results of the study also open the door for further studies of specific T-cell activation pathways in human populations. The unique canine breed structure makes dogs an excellent model for studying genetic diseases. Incidences of specific diseases are elevated in different breeds, indicating that a few genetic risk factors might have accumulated through drift or selective breeding.
A test for high uric acid in blood may be called for when your doctor suspects that you may be suffering from gout. Recurring gout attacks can lead to permanently damaged joints and damaged kidneys, so it's important always to get diagnosed by your doctor. Here, you'll discover what causes high uric acid, what blood and urine tests can reveal, and, a summary of both drug-based and natural treatments for gout. A blood test on its own will indicate measured levels of uric acid in your blood. This will tell the doctor whether you have higher-than-normal uric acid levels, and thus gout. But a combined test which measures the levels of uric acid in both your blood and your urine can give an indication whether it's your kidneys that aren't working efficiently enough, or, that there is too much "purines" being produced in your body in the first place.
Rheumatoid Arthritis Halted: Researcher Invents Nontoxic Drug That Forces Hyperactive Immune Cells To Die
A researcher from Northwestern University Feinberg School of Medicine has invented a novel way to halt and even reverse rheumatoid arthritis. He developed an imitation of a suicide molecule that floats undetected into overactive immune cells responsible for the disease. Whimsically referred to as Casper the Ghost, the stealthy molecule causes the immune cells to self-destruct. The approach, tested on mice, doesn't carry the health risks of current treatments. "This new therapy stopped the disease cold in 75 percent of the mice, " reported Harris Perlman, the lead author and an associate professor of medicine at Feinberg. "The best part was we didn't see any toxicity.
You'd think folks who've had knee replacement surgery -- finally able to walk and exercise without pain -- would lose weight instead of put on pounds, but surprisingly that's not the case, according to a University of Delaware study. Researchers Joseph Zeni and Lynn Snyder-Mackler in the Department of Physical Therapy in UD's College of Health Sciences found that patients typically drop weight in the first few weeks after total knee arthroplasty (TKA), but then the number on the scale starts creeping upward, with an average weight gain of 14 pounds in two years. The study, which was sponsored by the National Institutes of Health, is reported in the Jan.
Investigators have identified a biomarker that could help doctors select patients with rheumatoid arthritis who will benefit from therapy with drugs such as Enbrel, a tumor necrosis factor (TNF)-antagonist drug. The study, led by researchers at Hospital for Special Surgery in collaboration with rheumatologists at University of Southern California, appears in the February issue of the journal Arthritis & Rheumatism. "While our study was performed on a relatively small group of patients and will need to be confirmed in a larger cohort, the data are promising and may be clinically significant for the medical management of patients, " said Mary K.