When you get infection due to bacteria, you will immediately be put on antibiotics. These medications help to cure and manage bacterial infections and diseases. In fact, the number of fatalities has reduced ever since antibiotics were discovered. These medications kill or inhibit the growth of bacteria in the body and when used correctly, they have the potential to save lives. However, if antibiotics are used indiscriminately, they can wreak havoc in the body, including causing antibiotic resistant strains of bacteria. Some people are known to be allergic to antibiotics and the reaction they suffer from depends primarily on the type of antibiotic consumed and the quantity.
An allergy is the disorder of the immune system where the system ends up becoming extremely sensitive to certain substances which are normally considered harmless. Usually when bacteria, fungi or viruses enter the body, the immune system produces antibodies and certain chemicals to kill these organisms. In a person who is allergic, the immune system produces antibodies and chemicals to fight non-infectious substances. These substances are known as allergens and the body's reaction to allergens is known as allergic reaction. Medical science has still not been able to make headway when it comes to allergies. Researchers know that number of substances can cause allergic reactions but the exact cause of allergies is still not known.
A growing body of evidence points to the fact that one of the underlying causes of asthma and allergies is that children are too protected from infection. They are not developing an immune system robust enough to fight off simple allergies. Recent research involving almost two thousand patients showed that children who were given broad spectrum antibiotics for colds and chest complaints are three times more likely to develop asthma, eczema and hay fever later in life. The key to the allergic response is two types of cells produced by the immune system. The cells are involved in fighting off infections by stimulating the production of antibodies.
WHAT: A new study in human cells has singled out a molecule that specifically directs immune cells to develop the capability to produce an allergic response. The signaling molecule, called thymic stromal lymphopoietin (TSLP), is key to the development of allergic diseases such as asthma, atopic dermatitis (eczema), and food allergy. The study team, led by Yong-Jun Liu, M.D., Ph.D., at the University of Texas M.D. Anderson Cancer Center, Houston, focused on dendritic cells, immune cells that initiate the primary immune response. Dendritic cells come into contact with other immune cells known as T cells, causing them to develop into different subsets of T cells, including helper 1 (Th1) and helper 2 (Th2) cells.
Circassia Extends Its Clinical-Stage Portfolio With Phase II Trials Of T-Cell Vaccines Against House Dust Mite And Cat Allergies
Circassia Ltd, a specialty biopharmaceutical company focused on allergy, announced that it has initiated phase II clinical trials of its T-cell vaccines targeting house dust mite and cat allergies. With the start of these studies, and the ongoing trial of Circassia's ragweed allergy (hay fever) T-cell vaccine, the company now has three clinical development programmes in phase II. Each of these builds on earlier successful phase II results with the company's ToleroMune(R) technology, which scientifically validated the novel use of T-cell vaccines in the treatment of allergy, and identified the optimal dosing regimens to progress into late-stage development.
The journal Homeopathy has published a two part special issue focusing on biological models of homeopathy. The special issue highlights experiments on homeopathic treatments in biological models, ranging from whole animals and plants to cell cultures and enzymes, showing a remarkable range of findings. Homeopathy is a form of complementary medicine which is controversial because of its use of extremely dilute medicines. Although there is considerable clinical research, homeopathy remains the subject of a heated debate. The special issue makes an important contribution to this debate, by reviewing laboratory experiments with high dilutions.